Drug Rehab
نویسندگان
چکیده
Few medications are as infamous as thalidomide: in the late 1950’s the drug, prescribed to pregnant women as a mild sedative and morning sickness remedy, caused severe congenital malformations in tens of thousands of newborns. The case had significant ramifications for the drug industry, with agencies around the world, including the U.S. Food and Drug Administration, restructuring their rules for drug use and approval. In the ensuing years, the name thalidomide became synonymous with medical disaster and the need for safeguards in drug development. Yet, unexpectedly and without much fanfare, thalidomide is getting a second chance, proving its usefulness in treating diseases as disparate as cancer and leprosy. Indeed, due to its immunomodulatory and antiproliferative properties, thalidomide hasquietly become an important treatment option for multiplemyeloma.
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ورودعنوان ژورنال:
- Cell
دوره 159 شماره
صفحات -
تاریخ انتشار 2014